Hyperhidrosis treatment in Calgary

Excessive sweating diagnosisand treatment in Calgary.

Hyperhidrosis is sweating beyond what the body needs to regulate temperature. It affects about three percent of the population, most often the underarms, palms, soles and face, and it is treatable. At Rejuvenation Dermatology Calgary South, Dr. Paul Kuzel, a board-certified dermatologist, distinguishes primary from secondary hyperhidrosis and treats it with topical therapy, botulinum toxin, oral medication and device-based options.

14Years of training FRCPCRoyal College certified VPAlberta Society of Dermatologists
What it is

Sweat glands that fire beyond what the body needs.

Sweating is controlled by the sympathetic nervous system. In hyperhidrosis the glands are normal in number and structure, but the nerve signal to them is exaggerated, so they produce sweat in the absence of heat or exertion.

The mechanismEccrine sweat glands are activated by acetylcholine released from sympathetic nerve endings. In primary hyperhidrosis this signalling is overactive at specific sites, and is amplified by emotional stimuli. Every effective treatment interrupts the signal or blocks the gland.
Who it affectsPrimary hyperhidrosis usually begins in childhood or adolescence, runs in families in about half of cases, and affects men and women equally. It is focal, symmetrical, and stops during sleep. It is far more common than most patients realise, and far more treatable.
The impactHyperhidrosis is measured by its effect on daily life: the shirts changed, the handshakes avoided, the papers smudged, the shoes ruined. Surveys consistently rank its effect on quality of life alongside severe psoriasis and eczema. That impact is the indication for treatment.
Primary and secondary

The distinction that decides the work-up.

Most hyperhidrosis is primary and needs no investigation beyond a history and examination. A minority is secondary to a medical condition or a medication, and the pattern usually gives it away.

Most cases

Primary focal hyperhidrosis

Excessive sweating at one or more specific sites, symmetrical, present for six months or more, beginning before age twenty-five, absent during sleep, and often with a family history.

  • No underlying disease; no blood tests required in the typical case
  • Treated according to site and severity
Requires investigation

Secondary hyperhidrosis

Sweating that is generalised rather than focal, begins in adulthood, occurs during sleep, or is accompanied by weight loss, fever or other symptoms. Causes include thyroid disease, diabetes, menopause, infection, certain medications and, rarely, malignancy.

  • Investigated with a targeted history, examination and blood tests
  • Treatment is directed at the cause, with symptomatic treatment alongside
Common overlap

Medication-related sweating

Antidepressants, some diabetes medications, opioids and hormonal treatments can cause or worsen sweating. A medication review is part of every assessment, and a change is sometimes all that is needed.

Grading

Severity

Severity is graded on a four-point scale according to how much the sweating interferes with daily activities. Grades three and four indicate treatment beyond topical therapy is likely to be needed, and are the threshold at which botulinum toxin is considered.

Why a dermatologist

Exclusion of secondary causes, and the full range of treatment.

Hyperhidrosis is under-diagnosed and under-treated. Most patients have never been told it has a name, or that treatments beyond antiperspirant exist.

Excluding a causeGeneralised or night-time sweating warrants investigation. Dr. Kuzel takes the history that distinguishes primary from secondary hyperhidrosis and orders the tests that are needed, and no more.
Treatment by siteThe underarms, palms, soles, face and scalp each respond to different treatments. Botulinum toxin is the standard for the underarms; iontophoresis and toxin for the hands and feet; oral and topical anticholinergics for the face. The plan is assembled by site.
Botulinum toxin, correctly doneInjection for hyperhidrosis requires mapping the sweating area, a grid of injections at the correct depth, and appropriate dosing. Performed correctly, it stops underarm sweating for four to twelve months. Dr. Kuzel performs the injections himself.
CoverageAssessment of hyperhidrosis is medical dermatology, generally covered by Alberta Health Care with a referral. Botulinum toxin for severe primary axillary hyperhidrosis is a recognised medical indication, and many private drug plans cover the product with a prescription and prior authorisation. The injection fee and the treatment of other sites are quoted at consultation.
By site

Where it occurs, and what works there.

Each site has a first-line treatment and a next step. Most patients with hyperhidrosis at more than one site are treated at each according to its own ladder.

Site and first-line treatment

  • Underarms: prescription aluminium chloride, then botulinum toxin
  • Palms: iontophoresis or anticholinergic wipes, then botulinum toxin
  • Soles: iontophoresis or aluminium chloride, then botulinum toxin
  • Face and scalp: topical or oral anticholinergic medication
  • Generalised: oral anticholinergic medication after secondary causes are excluded
  • Compensatory sweating after surgery elsewhere: oral medication

Referrals and coverage

Assessment of hyperhidrosis is medical care, generally covered by Alberta Health Care with a referral from your family physician. Ask your doctor to refer you to Dr. Paul Kuzel at Rejuvenation Dermatology Calgary South, or have the referral faxed to (403) 225-2914.

Botulinum toxin for severe underarm sweating is a medical indication, and the product is covered by many private plans with prior authorisation. Call (403) 286-6888 and the team will advise on coverage and fees for your plan.

Treatment

A stepped approach, by site.

Treatment begins with the least invasive option effective for the site, and steps up according to response and severity.

First line

Prescription topical treatment

Aluminium chloride at prescription strength, applied to dry skin at night, blocks the sweat duct and is effective for mild to moderate underarm, hand and foot sweating. Topical anticholinergic wipes (glycopyrronium) reduce underarm sweating with once-daily use and are approved from age nine.

  • Irritation is the main side effect and is managed with technique and a mild steroid
  • Effect is maintained only while treatment continues
Moderate to severe

Botulinum toxin

A grid of small intradermal injections across the sweating area blocks the nerve signal to the glands. For the underarms, sweating stops within a week and the effect lasts four to twelve months, typically six to nine. Also used for palms, soles, forehead and scalp, with a nerve block or topical anaesthetic for the hands and feet.

  • Approved indication for severe primary axillary hyperhidrosis
  • Product often covered by private plans; injection fee quoted at consultation
Botox Dysport
Generalised, facial or multi-site

Oral anticholinergic medication

Glycopyrrolate or oxybutynin, taken daily, reduces sweating across the whole body. Useful for facial and scalp sweating, for generalised hyperhidrosis, and as an adjunct to site-directed treatment. Dose is titrated to balance benefit against dry mouth, the principal side effect.

  • Not suitable for patients with glaucoma or urinary retention
  • Reviewed at each visit
Hands and feet

Iontophoresis

The hands or feet are placed in shallow trays of tap water through which a low electrical current is passed for twenty to thirty minutes. Repeated several times a week initially, then weekly for maintenance. Home devices are available and effective for most patients with palmar or plantar hyperhidrosis.

Underarms, long-term

Microwave thermolysis

A device-based treatment that destroys underarm sweat glands with microwave energy, producing a lasting reduction in sweating after one or two sessions. Referral is arranged where this is appropriate and the patient prefers a permanent option to repeated injections.

Rarely required

Surgery

Endoscopic thoracic sympathectomy interrupts the nerve supply to the palms and is reserved for severe palmar hyperhidrosis that has failed all other treatment, because of the risk of compensatory sweating elsewhere. Referral to thoracic surgery is arranged in selected cases.

Your visit

Assessment, classification and a treatment plan.

The first visit establishes whether the hyperhidrosis is primary or secondary, grades its severity, and sets the treatment for each affected site. Botulinum toxin can often be scheduled at the same visit.

HistorySites, onset, pattern, night sweating, family history, medications, and what has been tried.
ExaminationThe affected sites, with a starch-iodine test where the sweating area needs to be mapped for injection.
InvestigationsBlood tests only where the pattern suggests a secondary cause.
Treatment planPrescription topical treatment, oral medication, iontophoresis instruction, or a botulinum toxin session, by site.
Follow-upFour to eight weeks for topical and oral treatment. Botulinum toxin is repeated when sweating returns.
What to expect

Expected outcomes.

Prescription topical treatment reduces sweating within one to two weeks in most patients with mild to moderate hyperhidrosis, and is continued for as long as it is needed. Botulinum toxin reduces underarm sweating by more than eighty percent in the large majority of patients, with onset within a week and a duration of four to twelve months, after which it is repeated.

Palms and soles respond to iontophoresis in most patients within two to three weeks of regular use, and to botulinum toxin where iontophoresis is insufficient. Oral medication reduces generalised and facial sweating within days, with the dose adjusted to limit dry mouth.

Primary hyperhidrosis is a lifelong tendency and treatment is maintained rather than completed. Many patients find that sweating lessens with age. Secondary hyperhidrosis resolves when the cause is treated.

1Week to onset of botulinum toxin 4 to 12Months of effect per session 1Physician managing the plan
Questions

Questions about excessive sweating, answered.

How do I know if my sweating is abnormal?

Sweating that occurs without heat or exertion, at specific sites, that interferes with daily activities, work or social life, and that has been present for six months or more is hyperhidrosis. If you change shirts during the day, avoid handshakes, or plan your clothing around sweating, it is worth assessing.

Is hyperhidrosis treatment covered by Alberta Health Care?

Assessment is medical dermatology and is generally covered with a referral. Prescriptions are covered by most drug plans. Botulinum toxin for severe underarm hyperhidrosis is a recognised medical indication and the product is covered by many private plans with prior authorisation; the injection fee is quoted at consultation. Treatment of other sites is quoted individually.

Do I need a referral?

For a covered assessment, a referral from a physician is the normal route, and it can be faxed to (403) 225-2914. If you do not have a family doctor or would rather not wait, call (403) 286-6888 and the team will advise.

How does Botox stop sweating?

Botulinum toxin blocks the release of acetylcholine, the chemical the nerves use to switch on sweat glands. Injected in a grid across the sweating area, it silences the glands in that area for several months. It does not affect sweating elsewhere and does not affect the body's ability to regulate temperature.

Does the injection hurt?

Underarm injections are brief and well tolerated; most patients describe a series of small pinches over a few minutes. The palms and soles are more sensitive and are numbed with a nerve block, topical anaesthetic or cold before injection.

How long does Botox for sweating last?

Four to twelve months, typically six to nine, for the underarms. The palms and soles tend toward the shorter end. Treatment is repeated when sweating returns, and many patients find the interval lengthens over successive treatments.

Are there tests for excessive sweating?

Primary focal hyperhidrosis is diagnosed on history and examination and needs no tests. Where the pattern suggests a secondary cause, blood tests for thyroid function, blood sugar and other markers are ordered. A starch-iodine test is used in clinic to map the sweating area before injection.

Will oral medication make me feel unwell?

The anticholinergic medications used for hyperhidrosis cause dry mouth in most patients, and can cause dry eyes, constipation or blurred vision at higher doses. The dose is started low and increased until sweating is controlled with acceptable side effects. They are avoided in patients with glaucoma or urinary retention.

Can children and teenagers be treated?

Yes. Hyperhidrosis commonly begins in adolescence, and topical treatments, including anticholinergic wipes, are approved for children. Iontophoresis is suitable for older children. Botulinum toxin is used in adolescents with severe underarm sweating on a case-by-case basis.

Who provides the care?

Dr. Paul Kuzel, MD FRCPC, a board-certified dermatologist and the founder and Medical Director of Rejuvenation Dermatology Calgary South. He sees patients in English and Czech.

Begin here

Book a consultation.

Book a consultation with Dr. Kuzel, or ask your family physician for a referral.

Rejuvenation Dermatology Calgary South
10201 Southport Rd SW #102
Calgary, AB T2W 4X9
Two blocks west of the Delta Hotel

(403) 286-6888
Referrals by fax: (403) 225-2914

Open seven days a week, with early mornings and evenings on weekdays.

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