Boey in Calgary

Try a neuromodulator for three weeks,not three months.

Boey is the first short-duration neurotoxin approved in Canada. It softens the frown line between the brows within a day or two and wears off on its own in two to three weeks, so you can see a result on your own face before deciding whether a longer-lasting treatment is for you. At Rejuvenation Dermatology Calgary South, Dr. Paul Kuzel, a board-certified dermatologist, assesses the face and performs every injection himself.

Join the Calgary waitlist Call (587) 293-2024
8 hrsEarliest visible change 2 to 3Weeks of effect FRCPCDermatologist injector
What it is

A type E toxin, built to leave quickly.

Boey (trenibotulinumtoxinE) is made by Allergan Aesthetics, the company behind Botox. Health Canada authorized it in June 2026 for moderate to severe frown lines between the eyebrows in adults, and Canada was the first country to approve it.

Same targetLike Botox and Dysport, Boey relaxes the small muscles that pull the brows together. The frown line softens because the muscle beneath it stops contracting.
Different serotypeBotox, Dysport and Nuceiva are botulinum toxin type A. Boey is type E. Type E is taken up by the nerve ending faster and cleared faster, so the effect arrives within hours to days and fades within weeks rather than months.
The point of itBoey is not a cheaper or weaker Botox. It is a preview. In Allergan's trials, 60% to 66% of patients met the responder threshold by day seven, and the effect had worn off by day 14 to 21. That short window is the feature.
Who it suits

The first step, for people who have never taken it.

Most people who ask about Botox have been thinking about it for years. The hesitation is rarely the needle. It is the idea of committing to a result they have never seen for three or four months. Boey removes that problem.

First time

Never had a neuromodulator

See how a softened frown line looks in your own mirror, in your own photos, for a few weeks. Then decide about Botox from experience rather than from someone else's before and after.

Afraid of frozen

Worried about looking done

The most common reason people never book. A treated frown line still moves; Boey lets you confirm that at low stakes, because if you disagree, it is gone in three weeks.

A date on the calendar

Wedding, reunion, photographs

Timed so the result is in place for the event and fades afterward. No decision about ongoing treatment required.

Not the right tool

Forehead, crow's feet, medical uses

Boey is approved for the frown line only. Forehead lines, crow's feet, jaw slimming, migraine and sweating remain Botox and Dysport territory, and Dr. Kuzel will say so at consultation.

All injectables
Boey or Botox

The same muscle, a different length of commitment.

Both are injected by Dr. Kuzel, both treat the frown line, and both come from the same manufacturer. The honest difference is how long you want to live with the result.

OnsetBoey: a visible change as early as 8 hours, building over the first few days. Botox: 3 to 5 days to begin, about two weeks to full effect.
DurationBoey: about two to three weeks. Botox: three to four months, then repeated for maintenance.
Approved areasBoey: frown lines between the brows. Botox: frown lines, forehead lines, crow's feet and a list of medical indications.
What comes nextBotox Cosmetic is the only neuromodulator clinically studied for use after Boey. If you like the preview, the transition is planned at the same visit, with the same injector.

Units of Boey are not interchangeable with units of Botox or any other toxin. Dosing is set by Dr. Kuzel at consultation.

Your visit

Fifteen minutes, and nothing to recover from.

Boey is a first-visit treatment. Consultation and injection usually happen at the same appointment.

ConsultationWhat bothers you about the frown line, what you are hoping to find out, and your health history, including any previous neuromodulator.
AssessmentDr. Kuzel examines the brow at rest and in motion and confirms that the frown line, and not a forehead or brow position problem, is what you are seeing.
Plan and consentDose, placement, what to expect over the next three weeks, and what the Botox path would look like if you want it afterward. Price confirmed before anything is injected.
InjectionA handful of small injections between the brows with a very fine needle. A few minutes. Straight back to your day.
ReviewA check at about day seven, when the effect peaks, and a conversation at three weeks about whether to continue with Botox, repeat Boey, or leave it there.
Aftercare and safety

What the trials found, and what we watch for.

Boey was studied in two placebo-controlled Phase 3 trials with 947 patients. Side effects were uncommon and mostly minor, but it is a prescription neurotoxin and is treated as one.

After treatment

  • Small bumps at the injection points for 20 to 30 minutes
  • Headache or tenderness at the site in some patients, reported no more often than with placebo
  • No rubbing the area and no lying flat for four hours; no strenuous exercise the same day
  • Eyelid or brow drooping was uncommon in the trials and resolves on its own; report it to the clinic
  • As with every botulinum toxin, spread beyond the treated area is rare but possible; muscle weakness, double vision or trouble swallowing or breathing need medical attention immediately
  • Not used in pregnancy, breastfeeding, infection at the site, or with a known allergy to any botulinum toxin product

Booking and fees

Boey is arriving at Canadian clinics through late 2026 and supply is limited at first. Pricing for Calgary South is confirmed before launch, and people on the waitlist hear first. No referral is needed.

Call (587) 293-2024 to join the waitlist by phone.

Questions

Questions about Boey, answered.

Is Boey available in Calgary now?

Health Canada authorized it in June 2026 and Allergan is rolling it out clinic by clinic. Rejuvenation Dermatology Calgary South is taking a waitlist, and waitlist members are offered the first appointments when stock arrives.

How fast does it work?

Some trial patients saw a change at 8 hours. Most reached the responder threshold by day seven. Expect the result to build over the first few days rather than appear all at once.

How long does it last?

About two to three weeks. In the trials the frown line was back to baseline between day 14 and day 21. That is by design: Boey is a preview, not a maintenance treatment.

Why would I choose a treatment that wears off so fast?

Because you have never seen the result on your own face. Boey lets you live with a softened frown line for a few weeks and then decide about Botox from experience. If you do not like it, it is gone.

Can I have Botox after Boey?

Yes. Botox Cosmetic is the only neuromodulator clinically studied for use after Boey. If you like the preview, Dr. Kuzel plans the transition at your review.

Can Boey treat my forehead or crow's feet?

No. It is approved for the frown line between the brows only. Other areas, and medical uses such as migraine and sweating, are treated with Botox or Dysport.

Does it hurt?

A brief pinch at each point with a very fine needle. Numbing cream is available if you prefer, though most patients do not use it.

How much does Boey cost in Calgary?

Pricing is confirmed before launch and shared with the waitlist first. Call (587) 293-2024 for the latest.

Who performs the injections?

Dr. Paul Kuzel, MD FRCPC, a board-certified dermatologist and the founder and Medical Director of Rejuvenation Dermatology Calgary South, performs all injections personally. He sees patients in English and Czech.

Further reading

If you want to go deeper.

Neuromodulators

BotoxThe three to four month treatment, and the next step after Boey. DysportA second type A option. InjectablesAll injectable treatments at the clinic.

Related

Migraine and TMJMedical uses of neuromodulators. Excessive sweatingAnother medical indication. SkinviveSkin quality rather than movement.

The clinic

Dr. Paul KuzelTraining, certification and approach. Calgary SouthLocation, hours and parking. All treatmentsEvery treatment offered at the clinic.
Begin here

Join the Boey waitlist.

Write "Boey waitlist" in your message and the clinic will confirm your place and contact you with pricing and dates before treatment opens to everyone else.

Join the waitlist Call (587) 293-2024

Rejuvenation Dermatology Calgary South
10201 Southport Rd SW #102
Calgary, AB T2W 4X9
Two blocks west of the Delta Hotel

(587) 293-2024
Referrals by fax: (403) 225-2914

Open seven days a week, with early mornings and evenings on weekdays.

Boey, Botox and Botox Cosmetic are trademarks of Allergan Aesthetics, an AbbVie company. This page is general information, not medical advice; suitability and dosing are determined at consultation.

Contact Rejuvenation Dermatology

Take the first step toward achieving healthy, radiant, and flawless skin. Contact Rejuvenation Medical Aesthetics today to schedule your personalized consultation and explore the advanced treatments tailored to your unique needs.